Overexposure out-of a woman fetus so you’re able to a lot of men hormonal when you’re nevertheless on mom’s uterus. This may be also on account of cancers creating male hormonal within the the mother.
Aromatase lack- Aromatase was an enzyme you to normally transforms men hormones so you can ladies hormonal. A lot of aromatase activity results in the newest overproduction from people hormone estrogen while you are their deficiency can cause 46, XX intersex, in which sufficient the hormone estrogen is not lead. This is simply not noticeable up until adolescence whenever such XX ladies initiate to demonstrate men attributes.
The new 46, XY individual has got the genotype out-of a masculine but the additional genitalia biguous or incompletely designed.